SAVI Brachytherapy


What is breast brachytherapy?


Breast brachytherapy is a contemporary standard of care that delivers radiation from inside the
breast, via a device placed through a surgical incision. The advantage is that radiation is delivered
only to the tissue immediately surrounding the tumor cavity, reducing treatment time from 6-7 weeks
to just 5 days or less and sparing more healthy tissue. It offers equivalent patient outcomes to older
treatment approaches such as external beam.


What is SAVI Brachy?


The SAVI applicator delivers a form of accelerated partial breast irradiation (APBI), a shortened
course of high-dose radiation for early-stage breast cancer patients following lumpectomy surgery. It
is a single-entry breast brachytherapy device that allows physicians to customize radiation based on
patient-specific anatomy. It has been in clinical use since 2006.



How does SAVI Brachy work?


The SAVI applicator is implanted into the lumpectomy cavity usually in an office-based procedure
after surgery. The applicator’s unique strut-based, open architecture design enables physicians toprecisely target radiation where it is needed most while minimizing exposure to healthy tissue.


What are the advantages of SAVI Brachy?


The SAVI applicator’s ability to customize radiation offers significant benefits, including:

  • Minimizes dose to normal tissue without sacrificing overall treatment coverage.
  • Eliminates skin spacing restrictions.3
  • Reduces the risk of fibrosis and symptomatic seroma.
  • Expands the number of women eligible for APBI.

What are the advantages of APBI for women?


  • Greater access by reducing therapy from 3 to 6 weeks to just 5 days or less. APBI means far
    less disruption to patients’ lives and families.
  • Less financial stress. Women who receive APBI usually avoid the out-of-town expenses and
    prolonged absence from work sometimes required with standard radiation therapy. Many
    patients are able to work and maintain other normal activities.
  • Better outcomes. With other forms of breast conservation therapy, women may experience
    damage to healthy tissue as a result of excessive radiation exposure to the skin, ribs, heart and
    lungs. SAVI reduces the risk of damage to healthy tissue and the chest wall and helps conserve
    future treatment options.